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Knowledge Graphs in Health
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== Technology Platforms == === Graph Databases === * '''Neo4j''' β leading graph database, extensive healthcare applications including MedQGraph (Temporal Medical Knowledge Graphs for AI-Driven Healthcare Insights). Snowflake now supports Neo4j graph analytics natively.<ref>Neo4j (2025): "MedQGraph: TMKGs for AI-Driven Healthcare Insights" β https://neo4j.com</ref> * '''GraphDB (Ontotext)''' β enterprise knowledge graph database, powers AIDAVA. Now part of Graphwise after merger with Semantic Web Company.<ref>PR Newswire (2024): "Semantic Web Company and Ontotext Merge to Create Graphwise" β https://www.prnewswire.com</ref> * '''AllegroGraph (Franz Inc.)'''' β semantic graph database widely used in life sciences. Supports RDF, SPARQL, and knowledge graph applications for clinical data integration.<ref>Franz Inc.: "AllegroGraph" β https://franz.com/agraph</ref> * '''Amazon Neptune''' β managed graph database, healthcare analytics use cases.<ref>AWS (2025): "Building health care agents using Amazon Bedrock AgentCore" β https://aws.amazon.com</ref> * '''Stardog''' β enterprise knowledge graph platform used in life sciences and pharma for data virtualization and reasoning.<ref>Databricks (2025): "Democratize insight with generative AI and knowledge graphs" β https://www.databricks.com</ref> * '''ArangoDB''' β multi-model database with graph capabilities used in healthcare analytics.<ref>MarketsandMarkets (2025): "Knowledge Graph Market Report 2025-2030" β https://www.marketsandmarkets.com</ref> * '''TigerGraph''' β scalable graph analytics for clinical data.<ref>Frontiers (2025): "A solution for combining multi-source heterogeneous data to construct enterprise knowledge graph" β https://www.frontiersin.org</ref> === Semantic Platforms === * '''PoolParty (Semantic Web Company / Graphwise)''' β semantic AI platform for health data classification and ontology management. Merged with Ontotext in 2024.<ref>TheRecursive (2024): "Graphwise β A Content Management Platform and a Graph Database Come Together" β https://therecursive.com</ref> * '''Elsevier Knowledge Graphs''' β life sciences knowledge graphs used for drug repurposing, linking literature, patents, and clinical data.<ref>Elsevier (2025): "How knowledge graphs can supercharge drug repurposing" β https://www.elsevier.com</ref> === LLM + Knowledge Graphs === Large language models are increasingly used to construct and query health knowledge graphs: * Nature: "Large language model powered knowledge graph construction for mental health exploration"<ref>Nature (2025) β https://www.nature.com</ref> * Frontiers: "Unlocking electronic health records: a hybrid graph RAG approach to safe clinical AI for patient QA"<ref>Frontiers (2025) β https://www.frontiersin.org</ref> * Anthropic: "Advancing Claude in healthcare and the life sciences"<ref>Anthropic (2025) β https://www.anthropic.com</ref> * WHO: "An epidemiological knowledge graph extracted from Disease Outbreak News"<ref>Nature (2025) β https://www.nature.com</ref> === FHIR + Graph Integration === * '''SMART on FHIR''' β open standards platform enabling third-party apps to access clinical data via FHIR APIs. Knowledge graph integration enables semantic queries across patient records.<ref>OCNJ Daily (2026): "10 Best FHIR Software Development Companies" β https://ocnjdaily.com</ref> * '''HL7 FHIR Bulk Data''' β enabling population-level data export for research. "What Bulk FHIR can do for quality measurement and more."<ref>Healthcare IT News (2025) β https://www.healthcareitnews.com</ref> * MedCity News: "Beyond the Buzzword: Why Semantic Interoperability is the Holy Grail for Digital Health"<ref>MedCity News (2025) β https://medcitynews.com</ref>
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